Chad Clark's Open Journal : 2007-03-26

1) Scientist retracts 5 years of work invalidated due to a programming bug.

http://boscoh.com/protein/a-sign-a-flipped-structure-and-a-scientific-flameout-of-epic-proportions

"In a short letter (barely over 300 words long) published in Science in the
very last issue of 2006, Geoffrey Chang, a crystallographer, retracted 3
Science articles, a Nature article, a PNAS article and a JMB article. The
sum of 5 years of work was destroyed, apparently, over a single sign error
in a data-processing program."